Protein Modification Reagents
Medchemexpress LLC (S,R,S)-AHPC-PEG1-N3 | 2101200-09-1 | 98.8% | 557.67 g/mol | C26H35N7O5S | 50 MG
(S,R,S)-AHPC-PEG1-N3 is a VHL E3 ligase ligand-linker conjugate that incorporates an (S,R,S)-AHPC VHL ligand and a single-unit polyethylene glycol (PEG1) linker terminated with an azide. It is designed as a building block for PROTAC assembly and for click-chemistry conjugations (CuAAC), enabling attachment of functional moieties to VHL ligands.
- Contains an azide functional group for copper-catalyzed azide-alkyne cycloaddition (CuAAC).
- Single-unit PEG linker provides improved solubility and controlled spacing between ligands.
- High purity (>98.7%) and molecular weight 557.67 g/mol for consistent characterization.
- Soluble in DMSO (100 mg/mL); insoluble in water (<0.1 mg/mL).
- Stable as a powder when stored at -20°C (up to 3 years) or 4°C (up to 2 years).
Medchemexpress LLC (S,R,S)-AHPC-PEG1-N3 | 2101200-09-1 | 98.8% | 557.67 g/mol | C26H35N7O5S | 1 G
(S,R,S)-AHPC-PEG1-N3 is an E3 ligase ligand-linker conjugate designed for use in PROTAC development and bioorthogonal labeling. It couples an AHPC-derived VHL ligand to a PEG1 spacer terminated with an azide for conjugation chemistry.
- Synthesized E3 ligase ligand-linker conjugate incorporating an AHPC VHL ligand.
- Peg1 spacer with a terminal azide enabling click chemistry conjugation.
- Molecular weight 557.67 g/mol and formula C26H35N7O5S.
- High purity (98.78%) suitable for chemical biology applications.
- Soluble in DMSO (100 mg/mL) and essentially insoluble in water.
- Supplied as a powder with recommended storage at -20°C for long-term stability.
Medchemexpress LLC (S,R,S)-AHPC-(C3-PEG)2-C6-Cl | 1835705-61-7 | MFCD31560481 | 95.0% | 749.44 g/mol | C39H61ClN4O6S | 50 MG
(S,R,S)-AHPC-(C3-PEG)2-C6-Cl is a VHL ligand-linker conjugate intended for use in proteolysis-targeting chimera (PROTAC) research. It couples an (S,R,S)-AHPC VHL-binding moiety to a short PEG linker and a chlorinated C6 terminus to enable E3 ligase recruitment and target degradation in cellular assays.
- VHL ligand-linker conjugate suitable for PROTAC applications.
- Demonstrated to induce degradation of GFP-HaloTag7 in cell-based assays.
- High solubility in DMSO and ethanol; in vivo formulation options available.
- Stored at -80°C, protected from light, under inert atmosphere.
- Molecular weight 749.44 g/mol; chemical formula C39H61ClN4O6S.
Medchemexpress LLC Dspe-peg-endo-bcn | 92.06% | 5000 (Average) | 5 MG
DSPE-PEG-endo-BCN (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. It can be used in drug delivery research.
Medchemexpress LLC DSPE-PEG-endo-BCN | 92.1% | 5000 (Average) | 1 MG
DSPE-PEG-endo-BCN (MW 5000) is a PEG lipid that can improve the delivery efficiency and tissue specificity of poorly soluble drugs. It can be used in drug delivery research.
- Improves delivery efficiency of poorly soluble drugs
- Enhances tissue specificity
- Suitable for drug delivery research
New England Biolabs, Inc. α-Lytic Protease - 20 µg
alpha-Lytic Protease (aLP) cleaves after Threonine (T), Alanine (A), Serine (S) and Valine (V) residues. Its specificity makes it an orthogonal and alternative protease to others commonly used in proteomics applications, including trypsin and chymotrypsin. Peptides generated by aLP are of similar average length to those of Trypsin.
eMolecules Bis-PEG11-NHS ester | Broadpharm | 123502-57-8 | MFCD30527397 | 796.817 | C34H56N2O19 | 95.000 | O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 500mg | 340377030
Bis-PEG11-NHS ester | Broadpharm | 123502-57-8 | MFCD30527397 | 796.817 | C34H56N2O19 | 95.000 | O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O | 500mg | 340377030
Medchemexpress LLC DMG-PEG-Mal (MW 2000) | 99.3% | 2000 (Average) | 25 MG
DMG-PEG-Mal (MW 2000) is a PEG lipid designed to enhance the delivery efficiency and tissue specificity of poorly soluble drugs. It is intended for use in drug delivery research.
- Improves the delivery efficiency of poorly soluble drugs.
- Enhances tissue specificity of poorly soluble drugs.
- Suitable for drug delivery research.
Medchemexpress LLC Dope-peg-dbco | 90.0% | 2000 | 5 MG
DOPE-PEG-DBCO (MW 2000) is a PEG lipid that includes DOPE and DBCO as functional groups. DOPE serves as a helper lipid in gene transfection, PEG is utilized in drug delivery systems, and DBCO can be employed for click chemistry.
- Helper lipid (DOPE) for gene transfection
- Used in drug delivery systems (PEG)
- Suitable for click chemistry (DBCO)
- Appearance: Oil
- Color: White to off-white
![eMolecules Broadpharm / SPDP-PEG-Mal MW 5000 / 500mg / 795361342 / BP-25331 / / / [null] / 482.570 / C20H26N4O6S2](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502472917.JPG-250.jpg)
eMolecules Broadpharm / SPDP-PEG-Mal MW 5000 / 500mg / 795361342 / BP-25331 / / / [null] / 482.570 / C20H26N4O6S2
Broadpharm / SPDP-PEG-Mal MW 5000 / 500mg / 795361342 / BP-25331 / / / [null] / 482.570 / C20H26N4O6S2